As the weather turns cold and dreary in much of the country, nothing sounds better than a Southern California getaway.

San Diego, with its sunny afternoon skies, laid-back surfer culture and top-notch brewery scene, attracts weekenders in search of the good life. While San Diego is a no-brainer for West Coasters, it's a bit of a trek for those who live east of the Mississippi. However, direct flights from most major U.S. cities and a little scheduling creativity make it a doable weekend trip for just about anyone. Follow our lead for the best way to make the most of your time in America's Finest City.

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